Comparison of Neutrophil to Lymphocyte Ratio in Obstructive Sleep Apnea Syndrome Phenotypes

Abstract

Objective: Our aim in this study was to compare the neutrophil to lymphocyte ratio (NLR) in rapid eye movement (REM) related obstructivesleep apnea (RRO) syndrome (OSAS) and position related OSAS (SRO) to habitual snorers (HSN) and try to find out the phenotype that increasesthe physical stress more.Methods: The patient charts and polysomnograms of all subjects referred to Yedikule medical center for chest diseases sleep departmentbetween June 2019 and January 2020 were reviewed and classified as RRO, SRO and HSN. Fasting blood tests were performed in the morningfollowing polysomnography. The phenotypes of OSAS were compared to each other by means of NLR.Results: A total number of 147 cases were reviewed. Forty eight cases were SRO, 49 cases were RRO and 50 were simple snorer. The NLR in RROwas statistically significant from those of SRO and HSN subgroups (p=0.001), whereas NLR in groups SRO and HSN were identical (p=0.650).Apnea Hypopnea index and O2 nadir in all groups were statistically significant from each other.Conclusion: Our data suggests that the REM related OSAS increases NLR as a predictor of inflammation, but NLR stays constant in Positionrelated OSAS and simple snorers.