Prevalence of Insulin Resistance in Type 1 Diabetes Mellitus and Its Correlation with Metabolic Parameters: The Double Trouble

Abstract

Objective: The phenotype of type 1 diabetes mellitus has changed over the last few decades. Little attention has been paid to the presence of insulin resistance in individuals with type 1 diabetes mellitus. The appearance of insulin resistance in type 1 diabetes mellitus patients has been labeled as “double diabetes.” This phenotype of double diabetes has been seen to have higher rate of microvascular as well as macrovascular complications. The aim of the current study was to estimate the burden of insulin resistance in patients with type 1 diabetes mellitus and its correlation with various metabolic parameters and microvascular complications. Materials and Methods: It was a cross-sectional study in which a total of 95 type 1 diabetes mellitus patients (children/adolescents (