Risk factors and Incidence of Catheter-Related Bloodstream Infections in a Tertiary Hospital ICU

Abstract

Objectives: Catheter-related bloodstream infections (CRBSI) are a major cause of morbidity and mortality in intensivecare unit (ICU) patients. The objective of this study was to assess the risk factors and incidence of catheter-relatedbloodstream infections in our hospital ICU.Methods: Over twelve months, a prospective observational study was performed in a 27-bed anesthesia-resuscitationand ICU, located in a 1000-bed education research hospital at Turkey. CRBSIs were recorded and analyzed.Results: Three-hundred seventeen patients were evaluated, and a total of 433 central venous catheters (CVCs) were insertedfor a duration >48 h. Patients' median age was 66 (IQRs=56-77), and 56.8% were male. The incidence of CRBSIwas 8.2 per 1000 catheter days. No significant relationship was found between several parameters: 1) age; 2) gender; 3)comorbid conditions; 4) catheter insertion site; and 5) main reason for ICU admission (p>0.05). Risk factors independentlyassociated with CRBSI were diabetes mellitus, long duration of catheterization, length of stay ICU and parenteral nutrition.The most common pathogens were Methicillin-resistant coagulase-negative staphylococci and Candida albicans.Conclusion: In our study, it was concluded that the duration of catheterization and the time of parenteral nutritiontreatment should be as short as possible. In addition, an association between CRBSIs and prolonged ICU stay andmortality was observed.