Prognostic Factors in Advanced Pancreatic Cancer: Single-Center, Real-World Data

Abstract

Objectives: Eighty percent of patients with pancreatic cancer present with unresectable/metastatic disease. Although clinical trials evaluating the efficacy of systemic treatments have been conducted in selected patient groups, reported survivals are short. In our study, we aimed to evaluate real-life data and factors affecting survival in patients with unresectable/ metastatic pancreatic cancer. Methods: The files of the patients who were followed up in our outpatient clinic with the diagnosis of pancreatic adenocarcinoma were evaluated retrospectively. A total of 151 patients had de-novo or recurrent, unresectable/metastatic disease. Variables that may affect the survival of these patients were recorded. Results: The median overall survival (OS) of patients receiving no systemic therapy for unresectable/metastatic disease and patients receiving chemotherapy was 2.4 months(m) and 9.3m, respectively (p