Relationship Between Ambulatory Blood Pressure Variability and Atherogenic Index of Plasma

Abstract

Objectives: In ambulatory blood pressure monitoring trials, non-dipper hypertensive patients had a worse cardiovascular outcome than dipper hypertension (HT) patients. However, no trials have been performed to inquire into the relationship between ambulatory blood pressure variability and coronary artery disease. In large-scale research, the atherogenic index of plasma has been found as a marker of coronary artery disease. This study inquired if there was a correlation between blood pressure variability and the atherogenic index of plasma. Materials and Methods: The study involved 158 hypertensive patients. Patients were distributed as non-dipper HT and dipper HT according to 24-hour ambulatory blood pressure follow-up. The dipper HT group consisted of 49 individuals, while the non-dipper HT group consisted of 109 patients. Biochemistry, hemogram and echocardiographic were examined. Results: Gender, previous diagnosis of HT, serum creatinine, hemoglobin and cholesterol, triglyceride levels were similar in both groups. The dipper HT group had more patients with diabetes (36.7% vs 13.8% p