Lipid profile in children with insulin dependent diabetes mellitus

Ceyhun DİZDARER, Çiğdem ECEVİT, Yasemin USLU, Tuğrul ÖZCAN, Tülay KAVAKLI

Abstract

This study was performed with 89 Type 1 Diabetic patients and 50 healthy children as the control group who were similar with age, sex, weight, height and pubertal status. We examined the changes in the lipid profile (Total cholesterol, HDL-C, LDL-C, VLDL, triglyceride, apo-A1, apo-B, lipoprotein electrophoresis) in children with Type 1 DM and differences from control group and also the correlations between (these lipids) and age, sex, puberty, duration of illness, HbA1c level. 45% (40 patients) of the patients were female and 55% (49 patients) were male in the diabetic group. The mean age of the diabetic group was 11.20 + 3.56 (3-17 years). Total cholesterol, LDL-C apo-B levels were higher in the diabetic patients, which was statistically significant (p

Özet

Bu çalışmada Tip 1 Diabetes Mellitus'lu 89 pediyatrik hasta ve yaş, cins, boy, kilo, puberte açısından benzer özelliklere sahip 50 sağlıklı çocukta, diyabette ortaya çıkan lipid profili (Total kolesterol, HDL-K, LDL-K, VLDL, trigliserid, apo Al, apo-B, lipoprotein elektroforezi) ile bunların kontrol grubundan farklılıkları ve birbirleri ile ve yaş, cinsiyet, puberte, hastalık süresi, HbA 1c seviyesi ile olan ilişkisi incelendi. Diyabetik grubun 40'ı (%45) kız, 49'u (% 55) erkek ve yaş ortalaması 11.20 ±3.56 yıl (3-17) idi. Total kolesterol, LDL-K ve apo-B hastalarımızda kontrol grubuna göre anlamlı yüksek saptandı, ayrıca birbirleri ile pozitif korele olduğu gösterildi (p