Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever

Ailesel Akdeniz Ateşi Olan Çocuk ve Ergenlerde Sağlıkla İlişkili Yaşam Kalitesinin Değerlendirilmesi

Burak Doğangün, Mehmet Yıldız, Özgür Kasapçopur, Kenan Barut, Sezgin Şahin, Gizem Durcan, Fatih Haslak, M. Tayyib Kadak, Amra Adrovic

Abstract

Objective: Health-related quality of life (HRQOL) is a concept that assesses the effects of physical symptoms, functional status, andcurrent illness on psychological and social functioning. In this study, we aimed to examine the quality of life in children and adolescentswith familial Mediterranean fever (FMF) according to personal and disease-related factors.Methods: A total of 257 children and adolescents with FMF aged 8–18 years were included in the study. The Juvenile Auto-inflammatory Disease Multidimensional Assessment Report was used for assessment of functional ability (self-report scale), pain (visual analog scale - VAS), therapeutic compliance, and HRQOL (physical, social, school, and emotional status). An increase in all subscale scores indicated a worsening.Results: The mean age of the patients was 12.4±2.63 years, and 132 (51.4%) of them were women. In adolescents, HRQOL-general,-social, -school, and -emotional scores were higher than children (p