Serum endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 levels in rheumatoid arthritis

Abstract

Purpose: To investigate the serum levels of adhesion molecules, soluble endothelial adhesion molecule-1 (sELAM-1) and soluble intercellular adhesion molecule-1 (sICAM-1), in active and inactive patients with rheumatoid arthritis (RA) and to find out their importance as a parameter in the active phase of the disease. Methods: sELAM-1 and sICAM-1 levels were measured in 30 active and 23 inactive RA patients, in 21 Behçet's disease (BD) patients and in 23 healthy subjects by using enzyme immunoassay (ELISA). Results: sELAM-1 levels of active RA patients were found to be increased than those of BD patients and healthy controls (p