Do inflammation and hormone parameters have effects on IVF results in patients with unexplained infertility?

Abstract

Aim: To invastigate the inflammatory process and hormone parameters as a result of underlying cause of unexplained infertility (UI)Metarial and Methods: In total 153 patients with UI who underwent to intracytoplasmic sperm injection (ICSI) were included in thestudy. The blood hormones levels were obtained on the 2nd or 3rd day of the menstruation. Other blood count examinations weretaken on the day of HCG administration. Relationship regarding embryo grade was also investigated.Results: Of those 153 patients, only 42 of them got pregnant. Mean maternal age was 29.08±3.5 and mean duration of the infertilitywas 8.19±3.1 years, respectively. There was no statistically significant difference between pregnancy rate, embriyo grade, and FSH,progesterone, fT3, fT4, TSH levels (p>0.05). Also no significant difference was found between pregnancy rate, embriyo grade andhemoglobin, hemotocrit, platelet, mean platelet volume, neutrophil, lymphocyte counts, neutrophil lymphocyte ratio and plateletlymphocyte ratio (PLR) (p>0.05). However, a significant difference was found between embriyo grade and estradiol values (p