Effects of epilepsy control following decompressive craniectomy on mortality and morbidity in epileptic patients with malignant MCA infarction

Abstract

Aim: The present study aims to investigate the effects of seizure or epilepsy formation on mortality and morbidity in epilepticpatients after craniectomy.Material and Methods: The patients were divided into the following groups: Group 1, those who had no seizures, but were routinelytreated with 3x100 mg of epanutin daily (n=6), Group 2, those who had at least one or multiple seizures and were initiated a secondantiepileptic drug in addition to 3x100 mg of epanutin daily (n=13), and Group 3, those who had multiple seizures and who weresedated or narcotized in addition to being treated with 3x100 mg of epanutin daily (n=7). All patients underwent decompressivecraniectomy within a maximum period of 48 hours and their characteristics such as age, gender, localization of infarct, hemiplegia,monoplegia, operation time, Glasgow coma and outcome scales were recorded.Results: According to the Glasgow Outcome Scale, 1 patient in Group 1, 8 patients in Group 2 and 6 patients in Group 3 died and therewas a signifiant increase in patient losses in Group 2 and Group 3 compared to Group 1 (p