Investigating neutrophil-to-eosinophil ratio and variations in eosinophil levels in epilepsy patients with generalized tonic-clonic seizures

Abstract

Aim: Neutrophil-to-eosinophil ratio (NER) shows inflammation, which can play a role in the development of some epilepsies andictogenesis. The current study aimed to investigate the NER and the variations in neutrophil and eosinophil levels in epilepsy patientswith generalized tonic-clonic seizures.Material and Methods: Epilepsy patients with generalized tonic-clonic seizures were retrospectively evaluated in the present study.Laboratory parameters of the patients in the acute (within 6 hours after the seizure) and subacute (on day 5 after the seizure) phaseswere compared.Results: 60 patients (30 males and 30 females) who had generalized tonic-clonic epileptic seizures were included in the study. Themedian neutrophil count and NER were signifiantly higher in the acute phase than in the subacute phase (p