The evaluation of the optic nerve in multiple sclerosis using MRI histogram analysis

Abstract

Aim: Comparison of optic nerve with healthy subjects by MRI histogram analysis in patients with multiple sclerosis (MS).Material and Methods: A total of 78 patients with age range of 39 ms (18-54), 27 females, 12 males and 39 healthy age range (19-54),26 females and 13 males (control group) were included in the study. The right optic nerve in the MS and control group was includedin the study. ROI was placed on the optic nerve from the images and numerical data were obtained by histogram analysis. Numericaldata were loaded into MATLAB program.Results: Mean, standard deviation, minimum, maximum, median, variance and entropy values were significantly higher in MSpatients than control group(p