Serum and salivary obestatin concentrations in thediagnosis of polycystic ovary syndrome

Abstract

Aim: : To measure obestatin levels in the blood and saliva samples of normal-weight patients with polycystic ovary syndrome(PCOS) in comparison with normal-weight healthy controls, and to determine whether there were relationships between blood and/or salivary obestatin levels and other measured parameters.Materials and Methods: Fifteen healthy women and 15 patients with PCOS, all of which had normal weight, were included in thestudy. Participants’ age, height, weight, menstrual characteristics, hormone levels, body mass index, waist/hip ratio, and modified Ferriman-Gallwey (FG) scores were recorded. Obestatin levels were measured in both fasting blood and saliva samples. Homeostasis Model Assessment (HOMA-IR) was used to predict insulin resistance.Results: In the PCOS group, menstrual cycle duration and FG scores were significantly higher (P-value,