Is there a relationship between serum paraoxonase level and epicardial fat tissue thickness?

Abstract

Objective: This study aimed to show the relationship between serum paraoxonase 1 level and the epicardial fat tissue thickness. Methods: Two hundred and seven patients without any atherosclerotic disease history were included in this cross-sectional observational study. Correlation analysis was performed to determine the correlation between epicardial fat tissue thickness, which was measured by echo- cardiography and serum paraoxonase 1 level. Also correlation analysis was performed to show correlation between patients’ clinical and laboratory findings and the level of serum paraoxonase 1 (PON 1) and the epicardial fat tissue thickness. Pearson and Spearman test were used for correlation analysis. Results: No linear correlation between epicardial fat tissue thickness and serum PON 1 found (correlation coefficient: -0.127, p=0.069). When epicardial fat tissue thickness were grouped as 7 mm and over, and below, and 5 mm and over, and below, serum PON 1 level were signifi- cantly lower in ≥7 mm group (PON1 : 168.9 U/L) than