Journals / Türk Geriatri Dergisi / 2020 / Cilt: 23 - Sayı: 4
INVESTIGATION OF THE RELATIONSHIP BETWEEN MORTALITY AND RED CELL DISTRIBUTION WIDTH, MEAN PLATELET VOLUME, PLATELET-TO-LYMPHOCYTE RATIO, AND NEUTROPHIL-TO-LYMPHOCYTE RATIO IN GERIATRIC PATIENTS
- Journal
- Türk Geriatri Dergisi
- Pages
- 424–433
- DOI
- —
Özet
Introduction: This study aimed to investigate the relationship between allcause mortality and the values of red-cell distribution width, mean platelet volume,platelet-to-lymphocyte ratio, and neutrophil-to-lymphocyte ratio in geriatricpatients who had become bedridden.Materials and Method: The retrospective study reviewed 1981 patients aged65–104 years who were bedridden and followed at University of Health Sciences,Antalya Training and Research Hospital Family Medicine Clinic from 2016 to 2018.Due to the effects on studied test parameters, patients with anemia were excludedfrom the study, and 898 patients included. The baseline variables red cell distributionwidth, mean platelet volume, platelet-to-lymphocyte ratio, and neutrophil-tolymphocyte ratio were compared between survivors and non-survivors.Results: Of the 898 patients, 141 (15.7%) died during follow-up. Mean red celldistribution width (15.7%), platelet-to-lymphocyte ratio (140.5), and neutrophilto-lymphocyte ratio (3.14) levels in non-survivors were statistically significantlyhigher than those of survivors (14.9%, p<0.001; 125, p=0.030; and 2.38, p<0.001,respectively). The retrospective follow-up revealed that red cell distribution width,platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio levels (17.6%,205.82, and 4.99, respectively) had increased during the last three months beforedeath, but this was not statistically significant. The results of univariate logisticregression analyses showed that mortality was positively associated with red celldistribution width and neutrophil-to-lymphocyte ratio. In a multivariate model, redcell distribution width was identified as an independent predictive factor associatedwith mortality.Conclusion: Red cell distribution width, platelet-to-lymphocyte ratio, andneutrophil-to-lymphocyte ratio may be strong predictors of mortality in patientswho have become bedridden, and alarms to take action for measures.