Vitamin D Deficiency and Radiological Findings in Adult Non-Cystic Fibrosis Bronchiectasis

Özet

OBJECTIVES: Vitamin D may play an important role in immunity and its defiiency has been related to increased respiratory infections.The aim of this study was to detect the prevalence of vitamin D defiiency and to investigate the relationship between radiological andclinical effects on adult bronchiectasis (BR) patients.MATERIALS AND METHODS: A total of 130 patients with BR and 73 healthy individuals (control group) were enrolled in this study.Radiological severity was assessed using Modifid Reiff Score.RESULTS: The mean age of patients was 41.9±9.1 years (range, 18–85). The mean 25-hydroxyvitamin D (25(OH)D) level was 14.7±9.6ng/mL in BR patients and 19.8±6.9 ng/mL in the control group (p=0.001). Moreover, 95 (73.1%) adult BR patients were categorized asvitamin D defiient. Patients in the vitamin D defiiency group had signifiantly higher Modifid Medical Research Council scores thanthose in the group without vitamin D defiiency (p=0.036) The mean modifid Reiff score was higher in the vitamin D defiient groupthan the without vitamin D defiiency group (6.9±3.8 vs 4.9± 2.7, p=0.001). Additionally, the vitamin D defiient group had lower forcedvital capacity% predicted value (p=0.02). This model showed that Reiff score (OR, 1.285[1.039–1.590]; p=0.021) was independentlyrelated to vitamin D defiiency.CONCLUSION: We found that vitamin D defiiency is commonly seen in adult BR patients in a stable period. Moreover, it might berelated to severe radiological fidings on chest computed tomography and worse lung functions.