Journals / Turkish Neurosurgery / 2012 / Cilt: 22 - Sayı: 6

Kronik myeloid lösemide subdural hematom olarak ortaya çıkan dural metastazlar

Dural metastases in chronic myeloid leukemia presenting as subdural hematoma

Pages
777–778
DOI
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Abstract

Subdural hematoma (SDH) has been reported in 0.5–4% of all intracranial metastatic tumors. Chronic SDH has been reported in intracranial metastases from both solid and haematological malignancies. Here we report recurrent SDH in a patient with chronic myeloid leukaemia (CML) following dural metastases. An elderly male patient a known case of CML was admitted to our casualty with symptoms of headache and altered sensorium and imaging revealed a large right fronto temporo parietal chronic SDH. This was surgically managed and histopathology of the duramater and subdural membrane confirmed infiltration with leukemic cells. The pathogenesis of chronic SDH in malignancies is multifactorial and this case report throws light on leukemic infiltration of duramater as a cause for chronic SDH other than coagulopathy.

Özet

Subdural hematom (SDH) tüm intrakraniyal metastatik tümörlerin %0,5-4’ünde bildirilmiştir. Kronik SDH hem solid hem hematolojik malignansilerden intrakraniyal metastazlarda bildirilmiştir. Burada kronik myeloid lösemili (KML) bir hastada dural metastazlardan sonra reküran SDH bildiriyoruz. Bilinen KML olgusu olan yaşlı bir erkek hasta acil servisimize başağrısı ve bilinçte değişiklikle geldi ve görüntüleme büyük bir sağ frontotemporoparietal kronik SDH gösterdi. Bu durum cerrahi olarak tedavi edildi ve duramater ve subdural membran histopatolojisi lösemik hücrelerle infiltrasyonu doğruladı. Malignansilerde kronik SDH patogenezi multifaktoriyaldir ve bu olgu raporu kronik SDH nedeni olarak koagülopati dışında duramaterin lösemik infiltrasyonunu aydınlatmaktadır.