Gelsolin levels in patients with bronchiolitis

Özet

Bronchiolitis is the leading cause of hospitalization in infants. Biomarkerscan show severity of the disease and help in clinical management. In thisstudy, the aim was to determine the clinical predictiveness of plasma gelsolinlevels (pGSN) in acute bronchiolitis.From December 2013 to May 2014, 52 patients with bronchiolitis (aged 0.05).Recent studies reported that pGSN levels can be used as a biomarker insepsis, inflammation and injuries. In this study, we have demonstrated thatpGSN level is not a predictive biomarker of bronchiolitis and its severity.Hence, we hypothesized that pGSN levels can be used in bacterial infectionsrather than viral infections as a biomarker.