Stevens-Johnson syndrome and toxic epidermal necrolysis: a report of six cases

Özet

Stevens-Johnson syndrome and toxic epidermal necrolysis are severe cutaneousadverse reactions commonly caused by exposure to drugs and can end upwith significant morbidity and mortality. We reported our experience withsix patients who were diagnosed with Stevens-Johnson Syndrome or ToxicEpidermal Necrolysis with a different clinical presentation. In patients, drugsand Mycoplasma pneumoniae infection were implicated as a trigger. IntravenousImmunoglobulin treatment was given to all patients, and intensive treatmentwas applied for skin and mucosal lesions. The median period of stay inhospital was 13.5 days. The most common long-term complication was ocularinvolvement. Among six patients, corneal epithelial defects occurred in onepatient. Consequently, ophthalmological evaluation should be performed bothat the time of diagnosis and before hospital discharge.