Impulse oscillometry reference values and correlation with predictors in Turkish preschool children

Özet

Impulse oscillometry (IOS) is a noninvasive, rapid technique requiringpassive cooperation that allows for evaluation of lung function through themeasurement of airway resistance and reactance. There are no availablereference values for Turkish children. This study is aimed to determine thereference values of IOS parameters and to study their correlation with height,weight, body mass index, and age as predictors in healthy Turkish preschoolchildren. Healthy children between 3-7 years of age who were selectedaccording to ERS/ATS criteria and followed at Kocaeli University outpatientclinic performed IOS. The correlation between the anthropometric predictorvariables and resistance and reactance at 5-20 hertz (R5-R20 and X5-X20),the respiratory impedance at 5 hertz (Z5), resistance area (AX) and resonancefrequency (Fres) were assessed by regression analysis and stepwise method.151 children (93 female) with the mean age of 67.9±16.2 months participatedin the study. Multilinear regression analysis for IOS values of all childrenrevealed that resistance was significantly correlated with height and reactancewas significantly correlated with age (p<0.05). For girls, height had a negativeeffect on R5-20, Z5, AX values, while age had a positive effect on X5-20 and anegative effect on Fres (p<0.05). For boys, weight had a negative effect on R5-20, Z5 values, while age had a positive effect on X15-20 and a negative effecton AX, Fres (p<0,05). This study provided reference values of IOS in healthyTurkish children that would be a useful guide for diagnosing and followingrespiratory diseases in preschool children.