Journals / Turkish Journal of Gastroenterology / 1997 / Cilt: 8 - Sayı: 2
Value of fibrinogen as a marker in gastrointestinal cancers
- Pages
- 194–196
- DOI
- —
Abstract
Increase of some coagulation factors and tendency to venous thrombosis have been reported in gastrointestinal cancers. In this study, plasma fibrino¬gen levels have been investigated in 24 patients with gastrointestinal cancer (esophageal, gastric and pan-cretic cancer). Significant increase has been found in the esophageal cancer group (p<0.01).Plasma fibrinogen levels were also elevated in two pancreatic cancer patients (9.52 and 6.45 gr/lt) but they were normal in gastric cancer patients. These results suggest that fib¬rinogen may be a useful tumor marker in some gas¬trointestinal cancers and further investigations are required in a large number of patients.
Özet
Gastrointestinal kanserlerde bazı koagülasyon faktörlerinde artış ve venöz tromboza eğilim bildirilmiş¬tir. Çalışmamızda mide özofagus ve pankreas kanseri teşhisleri konan toplam 24 vakada plazma fibrinojen düzeyleri araştırılmış ve özofagus kanseri grubunda an¬lamlı fibrinojen yüksekliği bulunmuştur(p 0.05).Bu sonuç¬lar fibrinojenin bazı gastrointestinal kanserlerde mar¬ker olma özelliğini göstermekte ve daha geniş sayıda hasta gruplarında konunun araştırılmasını önemli kıl¬maktadır.