Evaluation of hypertriglyceridemia-induced acute pancreatitis: A single tertiary care unit experience from Turkey

Özet

Background/Aims: This study aimed to determine the frequency of hypertriglyceridemia (HTG)-induced acute pancreatitis (AP) andassess different clinical and prognostic features in these patients.Materials and Methods: The patients who were hospitalized with AP due to HTG (HTG-AP) between January 2005 and December 2014were retrospectively evaluated in the clinic. The patients with AP due to non-HTG (non-HTG-AP) were also investigated during the sameperiod.Results: Of 635 patients with AP admitted to the clinic, 33 (5.2%) had HTG-related AP. Mean triglyceride levels were 2653 mg/dL (range:439-13700 mg/dL). Mean Ranson score at the time of admission was 1.5, and the APACHE II score was 4.63. The mean duration of hospitalization was 4.4 days (range: 2-14 days). One of these patients died on the sixth day of hospitalization due to multiple-organ failure.Patients with a triglyceride level of >1000 mg/dL were younger, had a longer hospital stay, and had a higher recurrence rate. Comparedwith non-HTG-AP, HTG-AP was observed at a younger age (57.4±17.3 vs. 37.6±14.8, p 1000 mg/dL.