Adverse factors responsible for below-normal platelet count after laparoscopic splenectomy and azygoportal disconnection

Özet

Background/Aims: Splenectomy is regarded as an effective curative treatment for thrombocytopenia caused by hypersplenism in patients with cirrhosis. However, in clinical practice, thrombocytopenia is not resolved by splenectomy in all patients. This study aimed toevaluate the adverse factors responsible for platelet (PLT) counts below the normal lower limit following laparoscopic splenectomy andazygoportal disconnection (LSD).Materials and Methods: We retrospectively evaluated the outcomes of 123 cirrhotic patients with portal hypertensive bleeding andsecondary hypersplenism, who underwent LSD and who had PLT counts 50 years and longitudinal spleen diameter ≤160 mm were threshold values for an increased risk of the PLT count <125×109/L at POM 3 after LSD.Conclusion: Age was an independent positive predictor and longitudinal spleen diameter an independent negative predictor of PLTcount <125×109/L at POM 3 after LSD.