Effect of Preoperative Uric Acid Level and Neutrophil / Lymphocyte Ratio on Preoperative and Postoperative Visual Analogue Pain Scores in Patients with Lumbar Disc Herniation: A Cross-Sectional Study

Özet

AIM: To determine the relationship between the serum urate (SU) level, neutrophil / lymphocyte ratio (NLR), and pain severity usingpreoperative and postoperative visual analogue scale (VAS) scores in patients with lumbar disc herniation (LDH).MATERIAL and METHODS: This single-center, cross-sectional study included 20 consecutive patients who were operated for LDHby the same surgeon. The patients’pre- and postoperative UA levels, NLRs, and intensity severity VAS scores were investigated.Preoperative magnetic resonance imaging (MRI) findings, serum UA levels, and neutrophil and lymphocyte counts were recorded.Pain severity was recorded preoperatively and at 6 months postoperatively. Effects of the preoperative SU levels and NLRs on thepre- and postoperative VAS scores were statistically assessed.RESULTS: Statistically significant positive correlation coefficients were determined between NLR and the preoperative andpostoperative VAS scores. Negative correlation coefficients were found between the SU levels and preoperative VAS scores; incontrast, positive correlation coefficients were found between the SU levels and the postoperative VAS scores.CONCLUSION: Our results demonstrate the importance of not ignoring the serum UA level and NLR in pre- and postoperative painin patients with LDH. Nevertheless, further extensive studies are warranted.