Characterizing the Intraoperative Microelectrode Recording-Induced Microlesion Effect on Motor Symptoms in Patients with Parkinson’s Disease Undergoing Deep Brain Stimulation of the Subthalamic Nucleus

Özet

AIM: To investigate microelectrode recording (MER)-induced microlesion effect (MLE) on the motor symptoms of 30 patients withParkinson’s disease (PD) who underwent deep brain stimulation of the subthalamic nucleus.MATERIAL and METHODS: MER-induced MLE was evaluated based on the difference between tremor, rigidity, and bradykinesiascores in the preoperative off-state and intraoperative state following MER and before test stimulation.RESULTS: MLE scores improved by 21.7% [left (L) side] and by 13.6% [right (R) side] from baseline (p 0.05).CONCLUSION: MER-induced MLE improved motor symptoms and was not correlated with the number of microelectrodes usedduring the procedure.