Journals / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 4

Relationship between urolithiasis and diastolic functions of the heart

Pages
574–579
DOI
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Abstract

Relationships between urolithiasis and cardiovascular disorders were evaluated in several studies. In this study, we aimed to investigate whether urolithiasis causes a decline in cardiac diastolic functions. Materials and methods: Seventy-seven consecutive patients and 40 age- and sex-matched controls were included in this study. Transthoracic echocardiography was performed for all patients. Results: There were 77 patients (mean age: 45 ± 14 years, 64% male) in the stone-formers group and 40 patients (mean age: 43 ± 12 years, 63% male) in the control group. Peak E wave velocity (0.67 ± 0.21 to 0.85 ± 0.18, P = 0.001) and E/A ratio (0.97 ± 0.21 to 1.37 ± 0.27, P = 0.001) were significantly lower in stone formers than in control patients. In addition, peak A wave velocity (0.74 ± 0.15 to 0.69 ± 0.14) was significantly higher in stone formers than control patients (P = 0.01). Diastolic dysfunction was more frequent in stone formers than control patients (P = 0.015). Conclusion: This study shows that there is a link between urolithiasis and cardiac diastolic dysfunction. Urolithiasis should therefore be recognized in evaluation of patients with diastolic dysfunction.

Özet

Relationships between urolithiasis and cardiovascular disorders were evaluated in several studies. In this study, we aimed to investigate whether urolithiasis causes a decline in cardiac diastolic functions. Materials and methods: Seventy-seven consecutive patients and 40 age- and sex-matched controls were included in this study. Transthoracic echocardiography was performed for all patients. Results: There were 77 patients (mean age: 45 ± 14 years, 64% male) in the stone-formers group and 40 patients (mean age: 43 ± 12 years, 63% male) in the control group. Peak E wave velocity (0.67 ± 0.21 to 0.85 ± 0.18, P = 0.001) and E/A ratio (0.97 ± 0.21 to 1.37 ± 0.27, P = 0.001) were significantly lower in stone formers than in control patients. In addition, peak A wave velocity (0.74 ± 0.15 to 0.69 ± 0.14) was significantly higher in stone formers than control patients (P = 0.01). Diastolic dysfunction was more frequent in stone formers than control patients (P = 0.015). Conclusion: This study shows that there is a link between urolithiasis and cardiac diastolic dysfunction. Urolithiasis should therefore be recognized in evaluation of patients with diastolic dysfunction.

Keywords: Key words: Urinary system, urolithiasis, diastolic dysfunction