Hyalinizing trabecular tumor of the thyroid gland

Özet

Hyalinizing trabecular tumor was first described by Carney et al. (1) in 1987 and is a rare benign tumor of thethyroid gland that shares some of the microscopic features of medullary and papillary thyroid carcinoma. Hyalinizingtrabecular tumor derives from follicular cells, and it is characterized by an apparent trabecular pattern andintratrabecular hyalinization. In this study, we present the case of a 40-year-old female patient with thyroid glandnodules, whose ultrasound results, clinical behavior, and fine-needle aspiration biopsy results were suspicious;the pathology after thyroidectomy indicated hyalinizing trabecular tumor. We aimed to show the role of clinicalbehavior, radiology, fine-needle aspiration, and histological and immunohistochemical analysis in the differentialdiagnosis of hyalinizing trabecular tumor. Hyalinizing trabecular tumor which can be confused with papillary andmedullar carcinoma of the thyroid gland, is mostly benign but some malignant and metastatic cases have beenreported. Therefore, diagnosis, treatment, and follow-up steps of Hyalinizing trabecular tumor should be plannedin consideration of a malignant potential.