Journals / Turkish Journal of Chemistry / 2004 / Cilt: 28 - Sayı: 4
Naphthoquinones from the Roots of Onosma argentatum Hub.-Mor. (Boraginaceae)
- Journal
- Turkish Journal of Chemistry
- Pages
- 451–454
- DOI
- —
Abstract
Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.
Özet
Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.