Comparison of outcomes in malignant vs. non-malignant ischemic priapism: 12-year experience from a tertiary center

Özet

Objective: Data on outcome of patients with ischemic priapism (IP) due to malignant causes are scant. Inthis study, we compared outcome of patients with malignant vs. non-malignant IP in adult North Indian men.Material and methods: We analyzed medical records of patients with IP who presented to a large tertiarycare referral center from August 2005 to July 2017.Results: Data of 71 patients were analyzed. The median age was 30 years (range 17-65). The average duration of symptoms was 4.39 days (range 1-10). Most common etiology was idiopathic in 29 (40.84%), chronicmyeloid leukemia (CML) in 24 (33.80%), and drug-induced in 15 patients. Thirty-eight patients underwentdistal shunts, while nine patients underwent proximal shunt procedure. Men with malignant priapism (CML)had significantly lower success rates with interventions, prolonged hospital stay, and higher complications(p<0.05). Most complications after shunt surgery were minor (Clavein grade 1 and 2). After shunt surgery,bleeding at shunt site was observed in 14 cases, and wound infection developed in five patients. Prevalenceof erectile dysfunction in patients at follow-up was high.Conclusion: Men with malignant priapism (CML) had significantly lower success rates with interventions,prolonged hospital stay, and higher complications than men with non-malignant priapism.