The Modified Urdu version of International Prostate Symptom Score: A psychometric validation study

Özet

Objective: The objective of the current study was to develop an Urdu version of the International ProstateSymptom Score (IPSS-U) and validate it for Pakistani patients suffering from lower urinary tract symptoms(LUTS).Material and Methods: IPSS-U was developed by a two-step forward and back translation and to evaluateits psychometric properties, a prospective study involving patients suffering from LUTS (n=267) wasconducted at Outpatient Urology Department, Mayo Hospital, Lahore, Pakistan. Internal consistency andreproducibility were assessed using Cronbach's alpha and the Intra-Class Correlation Coefficient (ICC).Moreover, exploratory, and confirmatory factor analyses were performed to determine dimensionality ofIPSS-U items.Results: Overall reliability of IPSS-U was satisfactory (Cronbach’s alpha=0.72, ICC of symptom questions=0.92 and ICC of QOL index=0.75). Exploratory factor analysis revealed that two factors were consistent,which together explained 59.8% of the variance. IPSS-U items 1, 3, 5 and 6 were components of thefirst factor whereas item 2, 4 and 7 were components of the second factor. All the items loaded high on theirfactors and there were no cross loadings. Moreover, confirmatory factor analysis also showed two-factormodel, with acceptable fitting patterns.Conclusion: IPSS-U is a valid and reliable non-gender specific instrument to assess the frequency and severityof LUTS in Urdu-speaking population.