Evaluation of Term Newborn Patients With Hypernatremic Dehydration

Özet

Aim: We aimed to evaluate the demographic, clinical, and laboratory findings and the managementof newborns with hypernatremic dehydration (HDH).Materials and Methods: A total of 85 term newborns with serum sodium (Na) levels higherthan 145 mEq/L who admitted to our hospital between January 2011 and December 2018 wereincluded in this study.Results: Among all cases, 54.1% were female infants with the mean birth weight, weight lossratio, and median age at diagnosis of 3095 ± 540 g, 13.6 ± 10%, and 8 (2-24) days, respectively.The most common presenting complaints were breastfeeding difficulties (90.5%), fever (63.5%),decreased urination (43.5%), jaundice (22.3%), and convulsion (15.3%). The mean sodium andpotassium, and median blood urea and creatinine levels on admission were 167.9 ± 13.4 mEq/L,5.4 ± 2.8 mmol/L, 213 mg/dL (11-476 mg/dL), and 2.4 mg/dL (0.52-9.96 mg/dL), respectively.There was metabolic acidosis in 67% and acute renal failure in 74.4% of patients, while peritonealdialysis was performed in 12 of them. There was a positive correlation between weight lossratio and admission age, serum urea, and creatinine levels; there was a negative correlationbetween weight loss and blood pH. Eight patients died (9.4%).Conclusions: In our study, serum urea, creatinine, potassium, metabolic acidosis levels, convulsion,and dialysis requirements at the time of admission of the newborns with HDH were foundto be higher in those who died compared to those who survived. Convulsion was a presentingcomplaint, and it was also observed during the treatment.