Cerebral sinovenous thrombosis in children: A single-center experience

Özet

Objective: The study aimed to evaluate the patients with a diagnosis of cerebral sinovenousthrombosis in terms of clinical findings, etiology and underlying risk factors, imaging findings,treatment, and prognosis in the long term.Materials and Methods: Medical records of 19 patients whose ages ranged between 0 daysand 17 years with clinical and radiological cerebral sinovenous thrombosis in Ege UniversityDepartment of Child Neurology were retrospectively evaluated.Results: Nine of nineteen cases were female (47.3%). The median age was 84 months (0-201months). The most common complaint at the presentation was headache (n=12) and the mostcommon physical examination finding was papilledema (n=11). In etiology, otitis/mastoiditis inthree cases, iron deficiency anemia in three cases, sinusitis in two cases, catheter use in fourcases, Behçet’s disease in three cases were determined. The most common observed geneticfactors causing thrombosis was methylenetetrahydrofolate reductase mutation. The transversesinus (68.4%) is the sinus where thrombosis is most frequently observed. As a result of an average follow-up of 12 months (2-72 months), hemiparesis (n=3/19, 15.7%) and epilepsy (n=5/19,26.3%) were recorded as sequelae findings, and no mortality was observed.Conclusion: In cases presenting with headache, evaluation of papilledema on funduscopic examination should not be skipped. Neurological imaging should be performed in the change ofconsciousness of poor feeding infants and children with infections in the head and neck area orunderlying chronic diseases. When cerebral sinovenous thrombosis is detected, anticoagulanttherapy should be started immediately.