Comparison of Voice Quality and Cost Effectiveness of Endoscopic Cordectomy Using Microdissection Electrodes with Laser Cordectomy and Radiotherapy

Özet

Objective: To compare the acoustic parameters andthe cost effectiveness achieved after endoscopic cordectomy using radiofrequency microdissection electrodes (ECRM) with those of transoral laser cordectomy and radiotherapy.Methods: The study included 81 disease-free patientspreviously treated for early larynx carcinoma (30 withECRM, 27 with transoral laser cordectomy, 24 withprimary radiotherapy). Post-treatment voice analysiswas performed in all patients. Additionally, the costeffectiveness of all treatment procedures was calculated.Results: The GRBAS (G: Grade, R: Roughness, B:Breathiness, A: Asthenia, and S: Strain) scale showeda significant difference between the groups (p 0.05 for all). Percent jitter, percent shimmer and fundamental frequency (F0) were significantlydifferent in the radiotherapy group than the ECRM andthe transoral laser cordectomy groups (p 0.05). The mean cost of the ECRM technique wasstatistically lower than the other treatment techniques(p<0.05). Moreover, the length of hospital stay afterECRM was statistically significantly shorter than wasafter laser cordectomy (p<0.05).Conclusion: Objective and perceptive voice analysisafter ECRM showed comparable results with transoral laser cordectomy, but poorer results than radiotherapy. Cost effectiveness of ECRM was found to bebetter than the other two treatment techniques