Journals / Turkish Journal of Cancer / 2000 / Cilt: 30 - Sayı: 2
Nasopharyngeal carcinoma case with glutathione-S-transferase-$\pi$ positivity by immunohistochemistry
- Journal
- Turkish Journal of Cancer
- Pages
- 86–88
- DOI
- —
Abstract
This report describes a case of stage IV undifferentiated nasopharyngeal carcinoma with glutathione S-transferase-$\pi$ positivity shown in the lymph node metastasis by immunohistochemistry. Chemotherapy resistance is a major problem in the treatment of patients with nasopharyngeal carcinoma and glutathione S-transferases contribute to the resistance. Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases
Özet
This report describes a case of stage IV undifferentiated nasopharyngeal carcinoma with glutathione S-transferase-$\pi$ positivity shown in the lymph node metastasis by immunohistochemistry. Chemotherapy resistance is a major problem in the treatment of patients with nasopharyngeal carcinoma and glutathione S-transferases contribute to the resistance. Detection of glutathione S-transferase-$\pi$ positivity by immunohistochemistry may affect therapy modalities in chemotherapy resistant cases