Seminoma arising in androgen insensitivity syndrome (testicular feminization syndrome): A case report

ABDULLAH FARUK ZORLU,Mustafa CENGİZ,Murat GÜRKAYNAK,Ferah YILDIZ,İ. Lale ATAHAN

Abstract

Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal woman with male karyotype (XY). The undescended testis may go into malignant transformation. The androgen insensitivity syndrome with malignant testicular disorder is very rare. A thirty-one year old female was admitted to the hospital with the complaint of primary amenorrhea. Clinical and laboratory investigation revealed testicular feminization syndrome with seminoma developed from intraabdominal undescended testis. Primary removal of the mass and postoperative radiotherapy were treatment of choice for the patient.

Özet

Keywords: Psödohermafroditizm,Radyoterapi,Androjen duyarsızlığı sendromu,Seminom