Natriuretic Peptides in Clinical Practice

Özet

Natriuretic peptides have long been introduced into clinical practice. These biomarkers have certainly been shown to provide useful informationin the diagnosis, prognosis and risk stratification in heart failure and also may have a role in the guidance of heart failure therapy. Although,there are some limitations in using of these markers such as lack of specificity, aging, renal dysfunction or obesity, among the huge number ofcandidates for heart failure biomarkers, only natriuretic peptides are currently widely used in daily clinical practice in heart failure. Recent heartfailure guidelines recognize natriuretic peptides as an essential tool in the new diagnostic and therapeutic algorithms. Furthermore, natriureticpeptides are not only used in the diagnosis or prognosis of heart failure, but also these biomarkers are referred to have some potential role inprimary prevention, cardio-oncology, advanced heart failure, assessment of response to cardiac resynchronization therapy, pulmonary arterialhypertension, acute coronary syndromes, atrial fibrillation and valvular heart disease. In this article, natriuretic peptides have been reviewed fortheir updated information and new recommendations in heart failure and also potential role of these biomarkers in the management of variousclinical conditions have been addressed in the form of expert opinion based on the available data in the literature. (Anatol J Cardiol 2019: 21Suppl 1; 1-40)