Journals / Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi / 2017 / Cilt: 8 - Sayı: 1
Antibiotic Sensitivity of the Escherichia Coli Strains Identified from Urine Samples
- Pages
- 38–42
- DOI
- —
Abstract
Objective: In this study, we aimed to evaluate the sensitivity of Fosfomycin and the other antibiotics against extended spectrum beta-lactamase (ESBL) negative and positive Escherichia Coli (E. Coli) strains. Material-Method: 100 ESBL positive and 100 ESBL negative E. Coli strains isolated from urine cultures were included to the study. Antibiotic sensitivity was determined by Kirby-Bauer disk diffusion method and /or automated Phoenix with 100 systems. ESBL was investigated with combined disk diffusion method. Results: Fosfomycin sensitivity was found as 96% and 98% in ESBL positive and negative E. Coli strains, respectively. It was found that, there was no İmipenem resistant strain, and the ESBL negative strains shown higher sensitivity rate than ESBL positive strains against the other antibiotics used in treatment. Conclusions: As a result, it was thought that, the Fosfomycin, which is also easy to use in a single dose, can be used in the treatment of uncomplicated urinary system infections caused by both ESBL positive and ESBL negative E. coli strains. We consider that the reasons why no early complication are the patient selection, careful follow-up, and treatment of the patients in a newly established transplantation center.
Özet
Amaç: Bu çalışmada, Fosfomisin ve diğer antibiyotiklerin genişlemiş spektrumlu beta-laktamaz (GSBL) negatif ve pozitif Escherichia Coli (E. Coli) suşlarına karşı duyarlılık oranları incelenmesi amaçlanmıştır.