N-acetyl cysteine and acute kidney injury after cardiac surger

Abstract

Acute kidney injury (AKI) is a very common and important complication of cardiac surgery. It is associated with severe complications including mortality. Cardiac surgery may induce oxidative stress and inflammation and both of these processes may be associated with AKI. N-acetyl cysteine (NAC) is a mucolytic agent and it has antioxidant and anti-inflammatory properties. Although positive results hav studies and meta-analyses. Currently available data do not support to recommend NAC for the prevention of AKI after cardiac surgery.