Assessment of Oxidative Stress and Antioxidant Levels in Chronic Periodontitis Patients

Özet

The aim of the present study was to assess the oxidative stress and antioxidant levels in periodontal patients. Chronic periodontitis patients and a control group were compared for SOD and MDA levels using TBARS and pyragallol auto-oxidation method and data was analysed. It was found that oxidative stress was higher in the study group when compared to control group and antioxidant levels were higher in the control group when compared to study group. A balance between the oxidation and anti-oxidant reactions is to be maintained in the body. The cells and the body are protected by antioxidants which guards them against the free radicals. In inflammatory conditions, this balance is broken. Hence, chronic periodontitis patients have high levels of oxidative stress and low levels of anti-oxidants. MDA and SOD can be used as a measure to find the oxidative stress in periodontal patients.