Journals / Üroloji Bülteni / 1999 / Cilt: 10 - Sayı: 3
Comparison between needle biopsy and radical prostatectomy grades in prostatic carcinoma
- Journal
- Üroloji Bülteni
- Pages
- 155–158
- DOI
- —
Abstract
Comparison Between Needle Biopsy And Radical Prostatectomy Grades In Prostatic Carcinoma-Objective: To investigate a probable discrepancy between Gleason scores of needle biopsy and radical prostatectomy specimens. Patients and Methods: Gleason scores of needle biopsy and radical prostatectomy specimens were compared in 40 patients operated between 1993 and 1997 for prostatic adenocarcinoma. Results: Overall consideration of patients revealed that 30 (75 %) patients had higher Gleason scores after radical prostatectomy than those reported in biopsy materials. The difference between biopsy and radical prostatectomy Gleason scores was statistically significant (p< 0.05). When Gleason scores were grouped as 2-4, 5-6 and 7-10 undergrading in biopsy specimens were noted in 25 (62.5 %) patients. There was no significant relation between the degree of differentiation and discrepancy between biopsy and prostatectomy Gleason scores (p> 0.05). Also no correlation was found between pathological stage and undergrading (p> 0.05). Conclusion: Undergrading in diagnostic biopsies for prostatic carcinoma has been determined in 75 % of patients. This should be considered in planning the treatment.
Özet
Biyopsi ile belirlenen Gleason skorlan ile radikal prostatektomi skorlan arasinda uyumsuzluk olup olmadigini arastirmak. Haqtalar ve Yontem: 1993 ile 1997 arasinda radikal prostatektomi yapilan 40 olguda biyopsi ve radikal prostatektomi Gleason skorlan karsilastirilmistir. BulgulanTum olgular gruplandmlmadan degerlendirildiglnde 40 olgunun 30'unda (% 75) radikal prostatektomi sonrasindaki Gleason skorlan biyopside bildirilenden yuksek bulunmustur. Biyopsi ve radikal prostatektomi Gleason skorlan arasindaki fark istatistiksel olarak anlamlidir (p 0.05): Yine biyopsi-prostatektomigrade farklan ile evre arasindaki iliski arastinldiginda anlamli korelasyon saptanmamistir (p>0.05). Sonug: igne biyopsisi ile olgulann % 75'inde radikal prostatektomiye gore dusukfifradelendirme yapildigi belirlenmis ve bu durumun tedavi plani yapilirken gozonune ahnmasi gerektigi dusunOlmiistur.