Journals / SSK İzmir Eğitim Hastanesi Tıp Dergisi / 2003 / Cilt: 9 - Sayı: 2
Osteoporosis at type 2 diabetic males
- Pages
- 41–43
- DOI
- —
Abstract
Type 1 diabetes mellitus causes a decrease in bone mass where as such as osteoporotic effect has not been demonstrated wıth type 2 diabetes mellitus. Osteoporosis is rarely seen among males and there has been no adeguate studies on this subject. 26 male patients wıth type 2 diabetes mellitus and 10 control cases ali aged betvveen 50-70 years were enrolled in the study. Bone mineral density was measured by dual energy X- ray absorbtıometry (DEXA). in adition, serum alkaline phosphatase, serum osteocalcin, serum procollagene-c levels as markers for bone formation; deoxypiridinoline ürine calcium, phosphorus and hydroxypyroline levels as markers for bone resorptıon were measured. There was no significant difference on comparing bone resorptıon and formation markers and BMD levels in the group of diabetic men to the control male group.
Özet
Tip 1 diabet kemik kütlesinde azalmaya neden olurken, tip 2 diabetin osteoporozu kolaylaştırıcı etkisi bulunmamaktadır. Erkeklerde osteoporoz nadir görülür ve tip 2 diyabetli erkeklerde osteoporoz konusunda yapılmış yeterli çalışma yoktur. 50-70 yaş arası Tip 2 diyabetli 26 erkek hastada ve 10 kontrol grubunda; DEXA ile kemik mineral dansitesi (BMD), kemik formasyon markerleri olan, serum alkalen fosfataz, osteokalsin, prokollagen -C, kemik rezorsiyon markerleri olan deoksipiridinolin, 24 saatlik idrarda kalsiyum, fosfor ve hidroksiprolin düzeylerine bakıldı. Her 2 grup arasında BMD, kemik rezorbsiyon ve formasyon markerleri arasında istatistiki bir anlamlılık saptamadık.