Comparison of Optical Coherence Tomography Angiography fi ndings in Diabetic Patients and Healthy Subjects

Özet

Purpose: The aim of this study is to compare superfi cial fl ow density (SFD), deep fl ow density (DFD), choriocapillaris fl ow density (CFD), superfi cial foveal avascular zone (SFAZ), deep foveal avascular zone (DFAZ), superfi cial vessel density (SVD) and deep vessel density (DVD) of advanced stage pre-proliferative Diabetic Retinopathy patients (PPDR) and normal subjects using optical coherence tomography angiography (OCTA) Materials and Methods: 40 eyes of 40 advanced stage PPDR patients and 40 eyes of 40 normal subjects were included in this prospective study as study and control groups respectively. Each subject underwent a comprehensive ophthalmic assessment, and OCTA image was taken. The right eye of each participant was used in the study. Results: There were no signifi cant differences between the study and control groups in respect of age and gender (p>0,05) (Table 1). The mean SFD, DFD, CFD, SFAZ, DFAZ, SVD and DVD values were 1230.92±111.56 mm2, 1185.33±156.15 mm2, 1860.6±56.17 mm2, 0.487±0.205 mm2, 0.646±0.240 mm2, % 47.50±3.15, % 52.38±3.54 in the diabetic group and 1520.22±38.31 mm2, 1596.25±79.83 mm2, 1962.7±26.96 mm2, 0.283±0.057 mm2, 0.340±0.054 mm2, % 54.23±3.27, % 60.72±3.39 in the control group, respectively (Table 1). There were statistically signifi cant differences between the two groups according to SFD, DFD, CFD, SFAZ, DFAZ, SVD and DVD measurements. Conclusion: Diabetic maculopathy and ischemia can be evaluated with OCTA. As being a rapid and non-invasive procedure, OCTA is particularly helpful in the follow-up and treatment of retinopathy in the early stages, especially in newly diagnosed diabetic patients.