Reactive arthritis

Abstract

Reactive arthritis (ReA) frequently is a sequel of gastrointestinal or genitourinary tract infections, previously identified as developing sterile inflammatory arthritis. When the pathogenesis of ReA is considered the most definite evidence on the role of microbial agents is based on the demonstration of microbial agents in the synovial fluid. Presence of wide range of difference in forms of immunological and clinical responses is depend on individual responses. Biochemical reactions of the cellular level, reflecting addition of host-microorganism relationship are recent advances in understanding ReA. Patients are usually young adults, the average age-range is between 30-40 years. The most obvious involvement of the disease is in the joints. Joint involvement can create aclinical spectrum from arthralgia to severe polyarthritis