Can neutrophil-lymphocyte ratio be a predictor of cerebral vasospasm in patients with subarachnoid hemorrhage?

Özet

This study aimed to investigate the relationship between neutrophil-lymphocyte ratio (NLR) and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (SAH). Materials and Methods The study was performed by retrospectively analyzing the data of 170 aneurysmal SAH patients who admitted to the intensive care unit of our hospital between 2011 and 2017. We investigated the ability of NLR values calculated from the blood samples taken at the time of admission to predict for vasospasm. Results Thirty-five percent of the patients developed vasospasm. NLR values were associated with the development of vasospasm (OR 1.15; 95% confidence interval, 1.09-1.22; p<0.0001). When the ability of NLR to predict for vasospasm was analyzed, the area under curve (AUC) of ROC curve was 0.776 (95% confidence interval: 0.70-0.85). The optimal cut-off point was 14.48 using the Youden index. The sensitivity and specificity for this cut-off point were 61.7% and 83.6%, respectively. Conclusion NLR can be used as an independent predictor of vasospasm development as a cheap and practical method, along with other predictive factors.