Malarial acute kidney injury

Abstract

Malaria is one among the top killer infectious diseases in the World. It is a parasitic disease of epidemiological importance in tropical countries and Malaria associated Acute Kidney Injury (MAKI) is emerging as a big Nephrological issue. We conducted a retrospective descriptive study to determine the demographic profile, incidence, clinical feature and outcome of acute kidney injury (AKI) due to Malaria in our institution from January 2010 to December 2014. Out of 138 Malaria positive cases admitted in our institution, the incidence of AKI was 15.7 %( 21). The main presenting features were fever (95.23%), jaundice (23.8%), vomiting (23.8%) and shortness of breath (14.28%) in cases with MAKI. 9.5 %( 13) of cases MAKI required some form of Renal Replacement Therapy (RRT). Two patients were managed with Sustained Low Efficiency Dialysis (SLED) and 11 with Intermittent Haemodialysis (IHD). The prognosis of AKI in Malaria is favourable with high quality intensive care, early diagnosis, prompt initiation of antimalarial therapy and RRTs in indicated cases