Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2017 / Cilt: 23 - Sayı: 6
Evaluation of Immunotherapeutic Effects of Aloe vera Polysaccharides Against Coccidiosis in Chicken
- Pages
- 895–901
- DOI
- —
Abstract
This study reports the immunotherapeutic effects of Aloe (A.) vera polysaccharides against coccidiosis in broiler chicken. For the purpose, polysaccharides were recovered from A. vera and analyzed by using HPLC. Three different hexose sugars including maltose, glucose and mannose were detected in hydrolyzed solution of A. vera. The extracted polysaccharides (graded doses) were evaluated for immunotherapeutic activities against coccidiosis in chicken. Results revealed that percent protection and daily weight gains were significantly higher (P<0.05) in chicken administered with A. vera polysaccharides as compared to control group. On the other hand, oocyst counts and lesion scores were lower (P<0.05) in polysaccharides administered chickens as compared to control. Moreover, anti-coccidial indices were also higher in chickens administered with polysaccharides (159.75-239.63) as compared to control (36.57). Except spleen, the organ-body weight ratios of all lymphoid organs of experimental and control groups were statistically similar (P>0.05). Based upon findings of this study, it was concluded that A. vera derived polysaccharides had immunotherapeutic activity against coccidiosis in chickens and might be further explored for its commercial feasibility for effective use in poultry industry to control avian coccidiosis.
Özet
Bu çalışma ile tavuklarda koksidiyoza karşı Aloe (A.) vera polisakkaritlerinin immunoterapötik etkisi rapor edilmektedir. Bu amaçla, A. vera'dan polisakkaritler elde edildi ve HPLC ile analizleri yapıldı. Maltoz, glikoz ve mannoz içeren üç farklı heksoz şekeri A. vera'nın hidrolize edilmiş solüsyonunda belirlendi. Ekstrakte edilen polisakkaritlerin (dereceli dozlarda) tavuklarda koksidiyoza karşı immunoterapötik etkisi araştırıldı. Sonuçlar; yüzde koruma ve günlük ağırlık kazanımının A. vera polisakkaritleri verilen tavuklarda kontrol grubuna oranla istatistiksel olarak daha yüksek olduğunu gösterdi (P 0.05). Çalışmanın bulgularına dayanılarak, A. vera polisakkaritlerinin tavuklarda koksidiyoza karşı immunoterapötik eksinin olduğu ve bu nedenle tavuklarda koksidiyozu kontrol altında tutabilmek amacıyla ticari kullanımının araştırılması gerektiği sonucuna varılmıştır.