Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2000 / Cilt: 6 - Sayı: 3
ART sikluslarında ovulasyon indüksiyonuna cevap alınamayan olguların değerlendirilmesi
- Pages
- 194–196
- DOI
- —
Abstract
OBJECTIVE: To evaluate the patients in our centre, during the last three years who underwent ovulation induction for ART and had poor responses. STUDY DESIGN: 64 patients who were admitted to the ART program of the Ege University Family Planning-lnfertility Research and Treatment Centre between 1997-1999 who were dismissed of the program due to low response were included in this study. These patients were evaluated according to their age, menstrual cycle, previous pelvic operations, baseline endocrine profile before the treatment, endocrine profile in the luteal phase, endometrial thickness and ovulation induction scheme. RESULTS: The mean age of the patient group was 36. 48 patients were over the age of 35 (75%). 59 patients had regular menstrual cycles while 5 patients were oligomenorrheic. While 20 of them had pelvic operations previously, 3 patients had pelvic endometriosis and one had had genital tuberculosis. Before starting ovulation induction the mean baseline FSH level was found as 15,1 mlU/ml, while the mean baseline E2 level was found as 60,6 pgr/ml. While basal endometrial thickness was measured as 6,1 mm. at the beginning of ovulation induction, it was 8 mm. at the time it was stopped. CONCLUSION: The cancellation of the patients during ovulation induction is correlated with advanced age. The FSH and E2 levels at the beginning of the menstrual cycle are helpful parameters in limiting patients for ART cycles.
Özet
1997-1999 yılları arasında merkezimizde ART uygulamasına alınmış ve ovulasyon indüksiyonuna cevapsızlık veya zayıf cevap nedeniyle tedavileri bırakılmış toplam 64 hasta incelendi. Hastaların ovulasyon indüksiyonundaki başarısızlıklarının ileri yaş faktörü ile bağlantılı olduğu görüldü. Siklus başlangıcındaki FSH ve LH seviyelerinin ART sikluslarına hasta seçiminde yardımcı bir parametre olduğuna karar verildi.