Journals / Glokom Katarakt / 2006 / Cilt: 1 - Sayı: 1
Evaluation of optic nerve head topography and retinal nerve fiber layer changes after trabeculectomy
- Journal
- Glokom Katarakt
- Pages
- 17–21
- DOI
- —
Abstract
Purpose: Assessment of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) changes following trabeculectomy with scanning laser ophthalmoscopy and scanning laser polarimetry in glaucoma patients. Materials and Methods: 16 eyes of 13 patients who had underwent trabeculectomy were evaluated with ONH topography (Topographic Scanning System, TopSS) and RNFL polarimetric analysis (NFA, GDx) preoperatively, and at 1 month, 3 months and 6 months postoperatively. TopSS and GDx parameters measured before and after trabeculectomy were compared using paired sample t-test and p<0.05 was considered to be statistically significant.. Results: After trabeculectomy, IOP reduced from 32.56±8.51 mmHg to 14.68±3.04 mmHg at 1 month, 13.82±3.04 mmHg at 3 months and 15.78±1.04 mmHg at 6 months. The mean neuroretinal rim area (NRRA) was found to be increased at 1 month (1.430 mm2±1.12), 3 months (1.540 mm2±1.15), 6 months (1.429 mm2±1.12) after trabeculectomy when compared with the initial measurement (1.367 mm2±1.16) (p<0.05). C/D ratio, half depth volume (1/2 DV) and half depth area (1/2 DA) decreased by months 1, 3 and 6 when compared with the preoperative measurements. None of the GDx parameters showed statistically significant changes following trabeculectomy(p>0,05). Discussion: Although NRRA and cup parameters were found to be significantly changed on topography, all of the GDx parameters including the average thickness, remained stable following trabeculectomy which could be explained by the removal of the mechanical effect of IOP on the ONH and the anterior movement of lamina cribrosa after a IOP decrease.
Özet
Amaç: Glokomlu olgularda trabekülektomi sonrası optik sinir başı (OSB) ve retina sinir lifi tabakasında (RSLT) meydana gelen değişikliklerin tarayıcı laser oftalmoskopi ve polarimetre ile değerlendirilmesi. Gereç ve Yöntem: Trabekülektomi yapılan 13 olgunun 16 gözü çalışmaya dahil edildi. Olguların ameliyat öncesi ve ameliyattan sonra 1. 3. ve 6. aylarda OSB topografisi TopSS (Topographic Scanning system), RSLT kalınlığı NFA GDx ile değerlendirildi.Ameliyat öncesi ve sonrası alınan TopSS ve GDx parametreleri eşleştirilmiş t-testi ile karşılaştırıldı ve p 0,05). Sonuç: Trabekülektomi sonrası GDx parametrelerinde değişiklik izlenmezken TopSS parametrelerinden NRRA ve c/d oranlarında meydana gelen değişiklikler, trabekülektomi’den sonra GİB düşüşü ile birlikte OSB üzerindeki mekanik basının kalkması ve lamina kribrozanın öne doğru yer değiştirmesi ile açıklanabilir.