Larynx cancers in Erzurum and its environment: Etiology and clinicopathologic features (62 cases)

Erzurum ve yöresindeki larinks kanserleri: Etiyoloji ve klinikopatolojik özellikler (62 olgu)

Abstract

Objective: This study was performed in order to evaluate the etiology and the clinicopathological features of larynx cancers in Erzurum and its environment. Methods: Sixty-two patients admitted to Radiation Oncology and Ear-Nose-Throat departments of Medical Faculty of Atatürk University between 1993 and 1997 were studied retrospectively. Results: Eighty-four percent of patient were admitted with hoarseness. 75% of the patients were cigarette addicts. The localization of the lesions was found to be as 57% glottic, 32% supraglottic, 8% subglottic and 3% transglottic. Histopathological findings were squamous cell cancer in 96%, adenosquamous cancer in 2% and spinocelluler cancer in 2% of the patients. Metastases were observed in four patients at application and during follow-up. Conclusion: Surgery was used in 16 patients, irradiation in 14 patients and both surgery and irradiation in 32 patients. Twenty-nine patients have still been followed-up regularly.

Özet

Amaç: Bu çalışma Erzurum ve yöresindeki larinks kanserlerinin etiyolojik ve kliniko-patolojik özelliklerini araştırmak amacıyla yapılmıştır. Yöntem: 1993-1997 yılları arasında Atatürk Üniversitesi Tıp Fakültesi Radyasyon Onkolojisi ve Kulak Burun Boğaz Anabilim Dallarına başvuran 62 hasta retrospektif olarak incelenmiştir. Bulgular: Hastaların başvuru semptomlarının başında (% 84) ses kısıklığı gelmektedir. Hastaların % 75’i sigara tiryakisiydi. Lokalizasyonlar % 57 glottik, % 32 supraglottik, % 8 subglottik ve % 3 transglottikti. Histopatolojik tanı % 96 olguda epidermoid kanser, % 2 olguda adeno-squamöz kanser ve % 2 olguda da spinoselüler kanser idi. Başvuru ve takipte 4 hastada metastaz saptanmıştır. Sonuç: Onaltı hastaya cerrahi, 14 hastaya radyoterapi ve 32 hastaya cerrahi ve radyoterapi uygulandı. Halen 29 hasta düzenli olarak kontrole gelmektedir.