Journals / Turkish Journal of Chemistry / 2008 / Cilt: 32 - Sayı: 1

Synthesis of New Bengazole Analogues and Their Antimicrobial Activity

Pages
125–130
DOI
—

Abstract

Bengazole A and bengazole B are 2 representatives out of a large family of marine metabolites isolated from a Jaspis sponge and display potent anti-fungal and anthelmintic activity as well as modest cytotoxic activity. This paper reports a short and efficient synthesis and microbiological evaluation of some new bengazole analogues.

Özet

Bengazole A and bengazole B are 2 representatives out of a large family of marine metabolites isolated from a Jaspis sponge and display potent anti-fungal and anthelmintic activity as well as modest cytotoxic activity. This paper reports a short and efficient synthesis and microbiological evaluation of some new bengazole analogues.

Keywords: Bengazole, lithiation, antimicrobial activity, cytotoxicity